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Updated: Dec 23, 2025

Fluorescence Anisotropy as a Tool to Study Protein-protein Interactions
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Published on: October 21, 2016

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硫黄-トリアゾール交換化学を用いたタンパク質の機能的なチロシン部位の結合

Jeffrey W Brulet1, Adam L Borne2, Kun Yuan1

  • 1Department of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States.

Journal of the American Chemical Society
|April 25, 2020
PubMed
まとめ

硫黄とトリアゾール交換 (SuTEx) の化学反応により,調節可能なタンパク質の改変が可能である. この多用途の共性化学は,標的タンパク質の機能障害のための多数のチロシンサイトを特定することによって,断片ベースのリガンド発見と化学プロテオミクスを前進させる.

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