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Updated: Dec 22, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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リバーシブルでリバーシブルでないコバルントPROTACを用いた効率的な標的分解

Ronen Gabizon1, Amit Shraga1, Paul Gehrtz1

  • 1Department of Organic Chemistry, The Weizmann Institute of Science, Rehovot 7610001, Israel.

Journal of the American Chemical Society
|May 6, 2020
PubMed
まとめ

リバーシブル共性PROTACは,従来の方法の限界を克服して,標的型タンパク質分解のための強力で選択的なアプローチを提供します. この研究により,ブルトン菌を分解する効果が示されました.

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