閉経後の女性の内生エストロゲンレベルとカルシウム摂取量. 皮質骨の測定値との関係
J A Cauley1, J P Gutai, L H Kuller
1Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261.
JAMA
|December 2, 1988
まとめ
生涯にわたる適切なカルシウム摂取量と十分なエストロゲン,特にエストロゲンのレベルは,閉経後の女性の骨密度の維持に不可欠です. これらの要因は,更年期後の骨の整合性をサポートするために一緒に働きます.
科学分野:
- エンドクリノロジー エンドクリノロジー
- 骨の生物学 骨の生物学
- 栄養科学とは,栄養科学である.
背景:
- 閉経後,骨の健康を維持することは非常に重要です.
- ホルモン変化とカルシウム摂取は,骨密度に影響を与える重要な要因です.
研究 の 目的:
- ホルモンレベル (アンドロゲン,エストロン) とカルシウム摂取量と,閉経後の女性の皮質骨密度との関係を調査する.
- 骨質のピーク発達と閉経後の骨の整合性に寄与する要因を特定する.
主な方法:
- 研究には174人の閉経後の女性が含まれていました.
- アンドロゲンホルモン,エストロンのレベル,および放射性骨密度との評価された関係.
- 骨密度に対するカルシウム摂取の影響を調べました.
主要な成果:
- エストロンのレベルは,放射性骨密度と独立した正の関係を示した.
- カルシウム摂取は,生涯にわたって高量のカルシウムを摂取した女性においてのみ,保護効果を示した.
- エストロンの高値とカルシウムの高摂取量は,添加効果を示し,骨密度を大幅に増加させた.
結論:
- 生涯にわたって十分なカルシウム摂取は,骨の健康に不可欠です.
- 十分な血清エストロゲンレベル,特にエストロンは,閉経後の骨密度の維持に不可欠です.
- 適切なカルシウム摂取と十分なエストロゲンレベルを組み合わせることで,閉経後の女性の骨密度を最適化することができます.
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