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Updated: Dec 21, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
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非競合するヒト中和抗体のペアは,COVID-19ウイルスの受容体ACE2への結合を阻害する

Yan Wu1,2, Feiran Wang3,4, Chenguang Shen3,5

  • 1Department of Pathogen Microbiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. wuy@biols.ac.cn gaofeng@tib.cas.cn gaof@im.ac.cn liulei3322@aliyun.com.

Science (New York, N.Y.)
|May 15, 2020
PubMed
まとめ

4つのヒト単一クローン抗体が分離され,B38とH4はSARS-CoV-2のスパイクタンパク質とACE2の結合を阻害した. これらの中和抗体は,COVID-19の治療法とワクチンの設計において有望である.

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