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Updated: Dec 21, 2025

Preparation of Nucleosome Core Particles Complexed with DNA Repair Factors for Cryo-Electron Microscopy Structural Determination
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Preparation of Nucleosome Core Particles Complexed with DNA Repair Factors for Cryo-Electron Microscopy Structural Determination

Published on: August 17, 2022

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人間のコヘシン-NIPBL-DNA複合体の冷凍-EM構造

Zhubing Shi1, Haishan Gao1, Xiao-Chen Bai2,3

  • 1Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|May 16, 2020
PubMed
まとめ

ヒトのコヘシンという 環状のATPアゼは DNAを閉じ込めることで ゲノムを組織します Cryo-EMはローダーNIPBLでその構造を明らかにし,DNAループの流出と姉妹染色体凝結メカニズムを説明します.

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