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Updated: Dec 20, 2025

Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications
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Microfluidic On-chip Capture-cycloaddition Reaction to Reversibly Immobilize Small Molecules or Multi-component Structures for Biosensor Applications

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バイオオートホーゴナル・テトラジン・カルバメート・クリーバージュ 高度反応性トランス-サイクロオクトン

Arthur H A M van Onzen1, Ron M Versteegen2, Freek J M Hoeben2

  • 1Tagworks Pharmaceuticals, Geert Grooteplein Zuid 10, 6525 GA Nijmegen, The Netherlands.

Journal of the American Chemical Society
|May 27, 2020
PubMed
まとめ

トランスサイクロオクトン (TCO) を利用してテトラジンリンクラーを活性化させ,急速な分裂とアミンの放出を可能にします. このTCO活性化テトラジンシステムは,化学および生物学的用途において,著しく速い反応速度を提供します.

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