新生児のウイルスの段階的な組み立ては,母乳育児によって調節されます
Guanxiang Liang1,2, Chunyu Zhao2, Huanjia Zhang2
1Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Nature
|May 29, 2020
まとめ
赤ちゃんの腸
科学分野:
- 微生物学
- ウイルス学
- 新生児の健康
背景:
- 赤ちゃんの腸は生まれながらにして ウイルスに感染していませんが 急速にコロニー化しています
- 新生児の胃腸に問題が生じることもあります
研究 の 目的:
- 新生児のウイルスコミュニティの段階的な組み立てを解明する.
- 乳幼児の腸内のウイルス集団の起源と動態を調査する.
主な方法:
- ウイルスが増殖し 微生物のコミュニティが 増殖する
- ウイルスのような粒子の光着色
- 標的型微生物学的分析
主要な成果:
- ウイルスの植民化は,先駆者バクテリアの細菌菌から始まり, 異なる段階で行われます.
- 1ヶ月後には 細菌菌が優勢になり 4ヶ月後には ヒトに感染するウイルスが増加します
- 授乳はウイルス集団の組成に影響し,配方栄養を摂取した乳児はヒトウイルスの豊富性が高くなります.
結論:
- 乳児の腸内ウイルスの植民化は 細菌菌によって開始され,後にヒトウイルスの影響を受けた段階的なプロセスです.
- 哺乳は乳児の腸内ウイルスを 調節する上で重要な役割を果たします
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