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Updated: Dec 20, 2025

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
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ステージとコンテキストは,複合腫瘍変異の機能を決定する

Alexander N Gorelick1,2, Francisco J Sánchez-Rivera3, Yanyan Cai4

  • 1Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|May 29, 2020
PubMed
まとめ

ヒト腫瘍の4分の"近くが 複合変異を備えています 複合変異は 癌の1つの遺伝子内の複数の変異と定義されます これらの複雑な遺伝子変異は 特定の進化的圧力から生じ,癌の発達と治療戦略に影響を与えます.

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