関連する実験動画

Updated: Dec 19, 2025

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus
05:01

Inducing Long-Term Plasticity of Intrinsic Neuronal Excitability in Neurons of the Dorsal Lateral Geniculate Nucleus

Published on: September 20, 2024

706

ニューロン不活性がLTPマシンを駆動してカリウムチャネルスプライシングとホメオスタティック・スパイクを拡大する

Boxing Li1, Benjamin S Suutari2, Simón(e) D. Sun2

  • 1Neuroscience Program, Guangdong Provincial Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine and The Fifth Affiliated Hospital, Sun Yat-sen University, Guangzhou 510810, China; Department of Neuroscience and Physiology, Neuroscience Institute, NYU Grossman Medical Center, New York, NY 10016, USA.

Cell
|June 4, 2020
PubMed
まとめ

慢性神経不活性症は,Nova-2経由でのBKチャネルスプライシングを変化させることで,運動ポテンシャル期間を恒常的に延長します. これは,神経刺激性とシナプス伝達に影響を与える,不活性とスプライシングの変化を結びつける新しいシナプス-核経路を含みます.

キーワード:
代替スプライシングBKチャンネルカMキナーゼノバ2アクションポテンシャル期間慢性的な活動不全ホメオスタシスシナプス活動

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