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Updated: Dec 19, 2025

Proteomics to Identify Proteins Interacting with P2X2 Ligand-Gated Cation Channels
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ヒトパネキシン1の構造は,イオン経路とゲートメカニズムを明らかにする

Zheng Ruan1, Ian J Orozco1, Juan Du2

  • 1Van Andel Institute, Grand Rapids, MI, USA.

Nature
|June 5, 2020
PubMed
まとめ

パネキシン1 (PANX1) チャンネル構造は二重ゲートメカニズムを示しています. アポトーシス中のカスパース分裂は,主要毛穴経由でATPの放出を解き放ち,カルベノクソロンはチャネル活動を阻害する.

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