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個々の腫瘍遺伝子の内にある複数の変異の風景と機能

Yuki Saito1,2, Junji Koya1, Mitsugu Araki3

  • 1Division of Molecular Oncology, National Cancer Center Research Institute, Tokyo, Japan.

Nature
|June 5, 2020
PubMed
まとめ

同じ腫瘍遺伝子の複数の誘導因子変異 (MMs) は,がんにおいて一般的であり,サンプルの9%に影響する. これらのMMは腫瘍性および薬物感受性を高め,がんの進化における重要なメカニズムを明らかにします.

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