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LEM2フェーズ分離は,ESCRTによる核エンベロープ改革を促進する

Alexander von Appen1, Dollie LaJoie2, Isabel E Johnson1

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco, CA, USA.

Nature
|June 5, 2020
PubMed
まとめ

核包膜リフォームは,LEM2タンパク質の凝縮により,核密封と適切な細胞分裂のためにESCRT複合体を活性化します. このプロセスは核の完全性を維持し DNAの損傷を防ぐために不可欠です

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