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Updated: Dec 19, 2025

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免疫グロブリンEのシアリレーションはアレルギー病原性の決定因子である

Kai-Ting C Shade1, Michelle E Conroy1, Nathaniel Washburn2

  • 1Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Nature
|June 6, 2020
PubMed
まとめ

シアリック酸の免疫グロブリンE (IgE) はピーナッツアレルギーで増加します. このシアル酸を除去すると,アレルギー反応が減少し,アレルギーの発症と重症性の重要な要因としてIgEグリコシル化が明らかになる.

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