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Updated: Dec 18, 2025

Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors
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Assessing Cellular Target Engagement by SHP2 PTPN11 Phosphatase Inhibitors

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TREM2信号経路の生理学,病理学,および潜在的な治療応用

Aleksandra Deczkowska1, Assaf Weiner1, Ido Amit1

  • 1Department of Immunology, Weizmann Institute, Rehovot 76100, Israel.

Cell
|June 13, 2020
PubMed
まとめ

TREM2受容体は,アルツハイマー病,代謝症候群,がんに関与する重要な免疫信号のハブです. TREM2シグナリングの理解は,これらの主要な疾患に対する新しい治療戦略の可能性を秘めています.

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