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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

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サイクロプロパンの σ-結合水酸化

Hiroki Kondo1, Shin Miyamura1, Kaoru Matsushita2

  • 1Institute of Transformative Bio-Molecules (WPI-ITbM) and Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.

Journal of the American Chemical Society
|June 17, 2020
PubMed
まとめ

研究者は,サイクロプロパンの水酸化のための新しいイリジウム触媒反応を開発し,シグマ結合を破って分岐アルキルボロナートを形成した. これは薬の発見や 自然製品の合成のための 複雑な分子への道を開きます

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A significant aspect of hydroboration–oxidation is the regio- and stereochemical outcome of the reaction.
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