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Updated: Dec 18, 2025

Visualizing the Conformational Dynamics of Membrane Receptors Using Single-Molecule FRET
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ディメリック細胞表面タンパク質に反応する感知・放出論理ゲート分子ネットワーク

Simona Angerani1, Nicolas Winssinger1

  • 1Department of Organic Chemistry, NCCR Chemical Biology, Faculty of Science, University of Geneva, 30 quai Ernest Ansermet, 1205 Geneva, Switzerland.

Journal of the American Chemical Society
|June 17, 2020
PubMed
まとめ

この研究では,ペプチド核酸 (PNA) を使用した新しいネットワークが導入され,二重タンパク質への反応として強力な細胞毒性物質を活性化します. この標的型アプローチは 特定のバイオマーカーに反応することで 癌治療の有望性を示しています

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