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ヒト化されたマウスと回復期の人間の研究により,SARS-CoV-2抗体カクテルが得られました

Johanna Hansen1, Alina Baum1, Kristen E Pascal1

  • 1Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA.

Science (New York, N.Y.)
|June 17, 2020
PubMed
まとめ

研究者は,人間化したマウスと回復中の患者を研究することで,SARS-CoV-2に対する強力な中和抗体を開発した. これらの抗体はスパイクタンパク質を標的にし,ウイルスの脱出変異体と戦うための治療的な抗体カクテルの有望な戦略を提供します.

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Single Nucleotide Polymorphisms-SNPs01:05

Single Nucleotide Polymorphisms-SNPs

A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...