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Updated: Dec 18, 2025

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
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Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

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還元サイクル/マニッヒ反応カスケードによるキロコリンCの簡潔でエナンチオ特異的な総合成

Vladislav G Lisnyak1, Scott A Snyder1

  • 1Department of Chemistry, University of Chicago, 5735 South Ellis Avenue, Chicago, Illinois 60637, United States.

Journal of the American Chemical Society
|June 20, 2020
PubMed
まとめ

研究者たちは 15段階の新しいプロセスを用いて キロコリンCという 独特なレディバッグのアルカロイドを合成しました この合成は9つの反応からなる 1つのコップのカスケードで 複雑な自然産物合成のための 先進的な有機化学の戦略を紹介しています

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Cycloaddition Reactions: Overview01:16

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Cycloadditions are one of the most valuable and effective synthesis routes to form cyclic compounds. These are concerted pericyclic reactions between two unsaturated compounds resulting in a cyclic product with two new σ bonds formed at the expense of π bonds. The [4 + 2] cycloaddition, known as the Diels–Alder reaction, is the most common. The other example is a [2 + 2] cycloaddition.
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