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Updated: Dec 18, 2025

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老化性CAR T細胞は老化に関連した病態を逆転させる

Corina Amor1,2, Judith Feucht3,4, Josef Leibold2

  • 1Louis V. Gerstner Jr Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Nature
|June 20, 2020
PubMed
まとめ

ウロキナーゼ型プラズミノゲン活性化受容体 (uPAR) を標的とする化学抗原受容体 (CAR) T細胞は老化細胞を効果的に排除する. この老化アプローチは,年齢関連の疾患の治療の可能性を示し,臨床前モデルでの生存率を改善します.

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