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Updated: Dec 18, 2025

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

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メタボリック・フィンガープリントリンク 腫瘍性PIK3CAと強化アラキドン酸由来エコサノイド

Nikos Koundouros1, Evdoxia Karali2, Aurelien Tripp2

  • 1Signalling and Cancer Metabolism Team, Division of Cancer Biology, The Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK; Division of Systems Medicine, Department of Metabolism Digestion and Reproduction, Imperial College London, London SW7 2AZ, UK.

Cell
|June 20, 2020
PubMed
まとめ

この研究は,がんを誘発するPIK3CA変異と,アラキドン酸代謝の変化を関連付けています. リン酸塩A2を阻害し,食事中の脂肪を制限することは,標的がん治療に有望である.

キーワード:
PIK3CAPKCζアラキドン酸cPLA2 について癌の代謝ダイエットエイコサノイド脂肪の制限イクナイフmTORC2 について

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