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Synthesis and Structure Determination of µ-Conotoxin PIIIA Isomers with Different Disulfide Connectivities
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Published on: October 2, 2018

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(-) - ピクロトキシニンの合成 末期の強い結合活性化

Steven W M Crossley1, Guanghu Tong1, Michael J Lambrecht1

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|June 24, 2020
PubMed
まとめ

神経毒性化合物 (-) - ピクロトキシン (PXN) の新しい効率的な合成が開発されました. この方法は,バイサイクルコアを構成し,最終的なラクトン構造を形成するために新しい二メチル化戦略を使用します.

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