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Updated: Jun 15, 2026

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma
12:03

Multi-photon Imaging of Tumor Cell Invasion in an Orthotopic Mouse Model of Oral Squamous Cell Carcinoma

Published on: July 25, 2011

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人間の状細胞がんにおける構成と空間構造の多様分析

Andrew L Ji1, Adam J Rubin2, Kim Thrane3

  • 1Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.

Cell
|June 25, 2020
PubMed
まとめ

この研究は,皮膚状細胞癌 (cSCC) の細胞構成を,ユニークな腫瘍細胞とその相互作用を特定することによって定義する. これらの発見は,cSCCの発達と潜在的な治療目標に関する新しい洞察を明らかにします.

キーワード:
CRISPRスクリーンMIBI について腫瘍内異質性マルチオミクスscRNA-seq について皮膚がん空間トランスクリプトミクス状細胞がん腫瘍免疫学腫瘍の微小環境

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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...
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Cancer arises from mutations in the critical genes that allow healthy cells to escape cell cycle regulation and acquire the ability to proliferate indefinitely. Though originating from a single mutation event in one of the originator cells, cancer progresses when the mutant cell lines continue to gain more and more mutations, and finally, become malignant. For example, chronic myelogenous leukemia (CML) develops initially as a non-lethal increase in white blood cells, which progressively...