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Updated: May 7, 2026

Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT
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Transnuclear Mice with Pre-defined T Cell Receptor Specificities Against Toxoplasma gondii Obtained Via SCNT

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トランスジェニックマウスでは,導入された機能的なT細胞受容体β遺伝子が,内生β遺伝子の発現を防ぐ

Y Uematsu1, S Ryser, Z Dembić

  • 1Basel Institute for Immunology, Switzerland.

Cell
|March 25, 1988
PubMed
まとめ

機能的なT細胞受容体β遺伝子を発現するトランス遺伝子マウスは,トランス遺伝子発現が内生β遺伝子の再配列を調節することを示した. これにより,同質のT細胞受容体が形成され,免疫反応では完全に機能し続けます.

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