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Updated: Dec 16, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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ティオペプチドの酵素マクロサイクリングにおけるバイクロフト・ゴーランド中間物質の検知

Jonathan W Bogart1, Nicholas J Kramer1, Aneta Turlik2

  • 1Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.

Journal of the American Chemical Society
|July 2, 2020
PubMed
まとめ

研究者はチオペプチドのバイオシンセシスの重要な中間物質であるサイクルヘミアミナルを特徴づけた. この発見は 酵素がこれらの複雑な自然産物の 核ヘテロサイクルを形成する方法を示しています

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