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Updated: Dec 16, 2025

Rapid In Vivo Fixation and Isolation of Translational Complexes from Eukaryotic Cells
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リボソームの衝突は 細胞の運命を調節する ストレス反応を誘発する

Colin Chih-Chien Wu1, Amy Peterson2, Boris Zinshteyn1

  • 1Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Cell
|July 2, 2020
PubMed
まとめ

リボソームの衝突は細胞のストレス反応を引き起こし,ストレス活性化タンパク質キナーゼ (SAPK) とGCN2経路を活性化します. ZAKタンパク質はこれらの衝突を検知し 即座に信号を発信します

キーワード:
SAPK について紫外線ZAKアミノ酸の飢餓統合ストレス反応リボソーム衝突

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