関連する実験動画

Updated: Dec 16, 2025

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate
04:48

A High-throughput Calcium-flux Assay to Study NMDA-receptors with Sensitivity to Glycine/D-serine and Glutamate

Published on: July 10, 2018

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哺乳類のNMDA受容体における機能的移行の構造的基礎

Tsung-Han Chou1, Nami Tajima1, Annabel Romero-Hernandez2

  • 1WM Keck Structural Biology Laboratory, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.

Cell
|July 2, 2020
PubMed
まとめ

N-メチル-D-アスパルテート受容体 (NMDARs) の活性化と抑制を理解することは,脳の機能の鍵です. 新しい構造データは,NMDARサブユニットへのリガンド結合がイオンチャネルゲートと競争抑制を制御する方法を明らかにしています.

キーワード:
N-メチル-D-アスパルテート受容体NMDAR抗体についてNMDARs についてX線結晶学チャンネル活性化および阻害メカニズムクリオ・エム電子冷凍顕微鏡リガンドゲートイオンチャネル

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