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Updated: Dec 16, 2025

Single Molecule Fluorescence Energy Transfer Study of Ribosome Protein Synthesis
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EF-Tu•GTPを用いたリボソームの冷凍-EMは,tRNAの校正を解明する

Anna B Loveland1, Gabriel Demo1,2, Andrei A Korostelev3

  • 1RNA Therapeutics Institute, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.

Nature
|July 3, 2020
PubMed
まとめ

リボソームは,ダイナミックな解読プロセスを用いて転送RNA (tRNA) を校正する. 延長因子EF-TuによるGTP水解によりtRNAが放出され,リボソームが正しいtRNAを閉じ込めるか,誤ったtRNAを拒絶することができる.

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