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Updated: Dec 16, 2025

Assessing Microglial Phagocytosis of Myelin Debris in vitro Under Repeated Magnetic Stimulation
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細胞外マトリクスのマイクログリアル再構成はシナプスの可塑性を促進する

Phi T Nguyen1, Leah C Dorman2, Simon Pan2

  • 1Department of Psychiatry and Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA; Biomedical Sciences Graduate Program, University of California, San Francisco, San Francisco, CA, USA.

Cell
|July 3, 2020
PubMed
まとめ

ニューロンは,記憶のためのシナプスの再構築にマイクログリアを導くためにインタールイキン-33 (IL-33) を放出します. このIL-33経路は学習と記憶に不可欠であり,年齢とともに衰えますが,IL-33では回復します.

キーワード:
マイクログリア,ヒポキャンプス,細胞外マトリックス,老化,記憶,デンドライト改造,インタールイキン-33

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