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Updated: Jul 26, 2026

Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation
12:48

Purification of the Membrane Compartment for Endoplasmic Reticulum-associated Degradation of Exogenous Antigens in Cross-presentation

Published on: August 21, 2017

溶解性タンパク質を抗原加工およびプレゼンテーションのクラスI経路に導入する

M W Moore1, F R Carbone, M J Bevan

  • 1Department of Immunology, Research Institute of Scripps Clinic, La Jolla, California 92037.

Cell
|September 9, 1988
PubMed
まとめ

細胞毒性Tリンパ球 (CTL) は,メジャー・ヒストコンパティビリティ・コンプレックス (MHC) のクラスI分子によって提示されるペプチドを認識する. オバルブミン (OVA) を細胞細胞質に直接注入すると,細胞外ではなく,CTL溶解に細胞を敏感にし,細胞内ペプチド処理経路を明らかにします.

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