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Updated: May 5, 2026

Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.
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Assessing the Innate Sensing of HIV-1 Infected CD4+ T Cells by Plasmacytoid Dendritic Cells Using an Ex vivo Co-culture System.

Published on: September 1, 2015

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HIV感染は,その受容体であるCD4の内細胞化を必要としません

P J Maddon1, J S McDougal, P R Clapham

  • 1Department of Biochemistry and Molecular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York 10032.

Cell
|September 9, 1988
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) は,CD4分子が内部化できるが,内細胞症ではなく,直接融合によって細胞に侵入する. この研究では,CD4変異体を使用してHIVの侵入メカニズムを調査しました.

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