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Updated: Dec 16, 2025

Author Spotlight: Advancing the Detection of Low-Frequency Mutations in Cancer Tissues
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TBL1XR1変異は,腫瘍に由来する記憶の運命を誘発することによって,外節リンパ腫を誘発する

Leandro Venturutti1, Matt Teater1, Andrew Zhai2

  • 1Division of Hematology/Oncology, Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.

Cell
|July 4, 2020
PubMed
まとめ

TBL1XR1の変異は,異常な不成熟記憶B細胞 (MB) を生成し,プラズマ細胞の発達を阻害することによって,攻撃的なB細胞リンパ腫を誘発する. リンパ腫の増殖を助長する 循環的な再侵入メカニズムにつながります

キーワード:
ABC-DLBCLについてBACH2 についてBCL6 についてTBL1XR1 について細胞の運命細胞の起源エクストラノダルリンパ腫発芽センターメモリB細胞

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