Bcl-2遺伝子は,血液形成細胞の生存を促進し,c-mycと協力して,pre-B細胞を不死化する

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Updated: Jul 30, 2026

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
10:21

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

D L Vaux1, S Cory, J M Adams

  • 1Walter and Eliza Hall Institute of Medical Research, PO Royal Melbourne Hospital, Victoria, Australia.

Nature
|September 29, 1988
PubMed
まとめ

葉っぱ性リンパ腫でよく見られるBCL-2遺伝子は,細胞の生存を促進する. MYC腫瘍遺伝子と結合すると,BCL-2はB細胞前駆体増殖と腫瘍形成を誘発する.

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