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Updated: May 8, 2026

Implementation of In Vitro Drug Resistance Assays: Maximizing the Potential for Uncovering Clinically Relevant Resistance Mechanisms
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プロテオゲノム分析により,肺腺癌の治療上の脆弱性が明らかになった

Michael A Gillette1, Shankha Satpathy2, Song Cao3

  • 1Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, 02142, USA; Division of Pulmonary and Critical Care Medicine, Massachusetts General Hospital, Boston, MA, 02115, USA.

Cell
|July 11, 2020
PubMed
まとめ

この研究では,プロテオゲノミクスを用いて肺腺がん (LUAD) を包括的に分析し,4つの異なるサブグループを明らかにし,治療上の脆弱性を特定しました. この発見は,LUADの生物学と潜在的な治療戦略に関する新しい洞察をもたらします.

キーワード:
CPTACアセチル化アデノカルシノーマゲノム学肺がんマススペクトロメトリーリン酸化タンパク質プロテオゲノミクスプロテオミクス

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