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DNAのN6メチラデニンは,発達初期にSATB1と対抗する.

  • 0Department of Genetics and Yale Stem Cell Center, Yale School of Medicine, New Haven, CT, USA.
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2020年7月17日

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
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