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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

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触媒性ヒドロキシクロプロパノール環開きカルボニラティブ・ラクトニゼーション

Xinpei Cai1, Weida Liang1, Mingxin Liu1

  • 1Department of Chemistry and Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.

Journal of the American Chemical Society
|July 21, 2020
PubMed
まとめ

パラジアム触媒による新しい反応は,ヒドロキシクロプロパノールからバイサイクルラクトンを効率的に生成します. この方法は自然製品の合成を含む温和な条件と広範なアプリケーションを提供します.

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