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Updated: Dec 14, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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合成バイオインフォマティック 自然産物 抗生物質 多種多様な作用形態

John Chu1, Bimal Koirala1, Nicholas Forelli1

  • 1Laboratory of Genetically Encoded Small Molecules, The Rockefeller University, 1230 York Avenue, New York, New York 10065, United States.

Journal of the American Chemical Society
|July 23, 2020
PubMed
まとめ

科学者は新しい抗生物質を発見するために,合成生物情報学的天然製品 (syn-BNP) のアプローチを開発しました. この方法により 抗菌剤耐性菌に対して有効な 新種の抗生物質が9種類特定され 抗菌剤耐性菌に対する希望が示されました

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