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Updated: Dec 14, 2025

Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production
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Retroviral Overexpression of CXCR4 on Murine B-1a Cells and Adoptive Transfer for Targeted B-1a Cell Migration to the Bone Marrow and IgM Production

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異なる経路からのシグナル入力で,B細胞変換が逆転する

Lai N Chan1, Mark A Murakami2,3, Mark E Robinson1

  • 1Department of Systems Biology, City of Hope Comprehensive Cancer Center, Monrovia, CA, USA.

Nature
|July 24, 2020
PubMed
まとめ

癌は変異が単一の腫瘍発生経路に 収束したときに発生します 単独では発生しません 抑制された経路を再活性化することで 変異を逆転させ,白血病の治療を強化できます

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