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Updated: Dec 14, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
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Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines

Published on: January 3, 2018

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フェニルエタノアミンN-メチルトランスフェラーゼの移行状態アナログ

Niusha Mahmoodi1, Rajesh K Harijan1, Vern L Schramm1

  • 1Department of Biochemistry, Albert Einstein College of Medicine, New York, New York 10461, United States.

Journal of the American Chemical Society
|July 25, 2020
PubMed
まとめ

フェニレタノアミンNメチルトランスフェラーゼ (PNMT) 阻害剤は,その移行状態を模倣するように設計された. 新しい阻害剤はナノモラー afinityを示し,PNMTに関連する状態のための新しい治療の可能性を提供します.

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