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Updated: Dec 13, 2025

Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
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Published on: December 23, 2020

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パパイン型のプロテアゼは,SARS-CoV-2 ウイルスの拡散と先天的な免疫を調節する

Donghyuk Shin1,2,3, Rukmini Mukherjee1,2, Diana Grewe2

  • 1Institute of Biochemistry II, Faculty of Medicine, Goethe University, Frankfurt, Germany.

Nature
|July 30, 2020
PubMed
まとめ

重症急性呼吸器症候群コロナウイルス2型 (SARS-CoV-2) パパイン型プロテアゼ (PLpro) はISG15を裂き,抗ウイルス免疫を阻害する. SARS-CoV-2 PLproを抑制すると,ウイルスの複製が抑制され,免疫反応が強化されます.

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