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Updated: Dec 13, 2025

High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
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細胞外タンパク質の分解のためのライソソーム標的キメラ

Steven M Banik1, Kayvon Pedram1, Simon Wisnovsky1

  • 1Department of Chemistry, Stanford University, Stanford, CA, USA.

Nature
|July 31, 2020
PubMed
まとめ

科学者は細胞外および膜タンパク質を分解する LYTAC (リソソーム標的キメラ) を開発しました この新しいプラットフォームは 以前は治療法で利用できなかった タンパク質をターゲットにすることで 癌や自己免疫疾患などの 治療の可能性を広げています

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