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Updated: Dec 13, 2025

Assessment of the Synaptic Interface of Primary Human T Cells from Peripheral Blood and Lymphoid Tissue
06:27

Assessment of the Synaptic Interface of Primary Human T Cells from Peripheral Blood and Lymphoid Tissue

Published on: July 30, 2018

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主要なヒトT細胞におけるエレクトロフィール-システイン相互作用の活動主導の地図

Ekaterina V Vinogradova1, Xiaoyu Zhang1, David Remillard1

  • 1Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.

Cell
|July 31, 2020
PubMed
まとめ

科学者はヒトのT細胞に 3,000種類以上の 感電性システインをマッピングしました これらの発見は,免疫反応や疾患を調節する化学探査機や治療薬の開発の潜在的なターゲットを示しています.

キーワード:
BIRC3 についてITK についてT細胞活動に基づくタンパク質プロファイリング化学プロテオミクスコバランスシステインエレクトロフィール人間タンパク質の分解

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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...
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