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Updated: Dec 13, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators

Published on: February 20, 2018

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家族Aと家族BのGPCRによるGタンパク質活性化の違いに関する構造的洞察

Daniel Hilger1, Kaavya Krishna Kumar1, Hongli Hu1,2

  • 1Department of Molecular and Cellular Physiology, Stanford University School of Medicine, 279 Campus Drive, Stanford, CA 94305, USA.

Science (New York, N.Y.)
|August 1, 2020
PubMed
まとめ

家族BのGタンパク質結合受容体 (GPCR) は,グルカゴン受容体と同様に,家族Aの受容体よりも遅いシグナリングを活性化させる. これは炭水化物の代謝の調節に影響します.

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