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関連する概念動画

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Accessory Structures of the Skin: Sebaceous Glands01:21

Accessory Structures of the Skin: Sebaceous Glands

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A sebaceous gland is a type of oil gland found almost all over the skin ( except palms and soles) and helps lubricate and waterproof the skin and hair. Most sebaceous glands are associated with hair follicles. They generate and excrete sebum, a mixture of lipids, onto the skin surface, thereby naturally lubricating the dry and dead layer of keratinized cells of the stratum corneum, keeping it pliable.
These glands that produce the oils on the skin and hair are holocrine glands. The mature...
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
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Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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アトピー性皮膚炎

Sinéad M Langan1, Alan D Irvine2, Stephan Weidinger3

  • 1Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust, London, UK; Health Data Research UK, London, UK.

Lancet (London, England)
|August 3, 2020
PubMed
まとめ
この要約は機械生成です。

アトピー性皮膚炎は 皮膚の炎症性疾患で や病変を引き起こし あらゆる年齢に影響を及ぼし 他のアレルギーや精神的健康問題と関連しています 広範囲 に 広がっ て いる この 皮膚 病 の より 良い 治療 と 制御 に つい て の 進歩 は 希望 を 持っ て い ます.

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科学分野:

  • 皮膚科
  • 免疫学
  • 遺伝学

背景:

  • アトピー性皮膚炎は,再発性湿疹性病変と激しいを伴う一般的な炎症性皮膚疾患です.
  • 精神社会的な影響があり 世界的に皮膚疾患の重荷を 引き起こす主な原因です
  • 併発症には食物アレルギー,喘息,アレルギー性鼻炎,精神疾患などがあります.

研究 の 目的:

  • アトピー性皮膚炎の理解における最近の進歩をまとめます
  • これらの進歩が病気の予防と管理に及ぼす影響について議論する.
  • アトピー性皮膚炎の将来的な研究方向性を強調するために

主な方法:

  • アトピー性皮膚炎の病理学と治療に関する最新の科学文献のレビュー
  • 遺伝子,表皮,免疫経路の関与に関する情報の合成.
  • 新しい標的治療法とその可能性についての議論

主要な成果:

  • アトピー性皮膚炎の病理学には,遺伝的傾向,表皮機能障害,および2型メカニズムが支配的な複雑な免疫経路が含まれます.
  • 現在 治療法がないにもかかわらず 革新的な標的治療法により 深刻な症例でも 病気をコントロールできる可能性が示されています
  • この病気の理解は進歩し,予防と管理の戦略に情報を与えています.

結論:

  • アトピー性皮膚炎は複雑な多因子疾患で,世界的に大きな影響を及ぼします.
  • 免疫経路と遺伝学の進歩は 新しい治療法への道を開いています
  • アトピー性皮膚炎の効果的な予防と長期的な管理戦略の開発には 将来の研究が不可欠です