幼少期の逆境と成人期の死亡率の軌跡:人口ベースのコホート研究
Naja H Rod1, Jessica Bengtsson1, Esben Budtz-Jørgensen2
1Section of Epidemiology, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Lancet (London, England)
|August 18, 2020
まとめ
貧困や家族の喪失など 子供の頃の逆境は 早期の成人期における死亡リスクを高めます 複数の逆境を経験した小グループでは リスクが著しく高くなり 深刻な公衆衛生上の懸念を示した.
科学分野:
- 公衆衛生
- 流行病学について
- 発達心理学
背景:
- 幼少期は 重要な発達期で 悪い経験は 健康に長期的な影響を 及ぼします
- 幼少期の不良体験 (ACE) は正常な発達を妨害し,後の健康問題に対する脆弱性を高めます.
研究 の 目的:
- 幼少期の不良体験の軌跡を記述する.
- これらの経路と早期の成人の死亡率との関連を調査する.
主な方法:
- デンマーク全国の登録 (1980年−2015年) を用いた人口ベースのコホート研究.
- 生まれてから34歳までのデータを分析しました
- グループベースの多軌道のクラスタリングと生存分析 (コックスとアレンモデル) を利用した.
主要な成果:
- 5つの異なる 幼少期の逆境の軌跡が 特定されました
- 物質的欠乏や喪失/喪失の脅威を経験した子どもは,死亡リスクが適度に高かった.
- 多重の逆境を体験した小さなグループ (3%) は,事故,自殺,がんを主な原因として,4.54倍高い死亡リスクに直面しました.
結論:
- デンマークの子供の半分近くが 逆境を経験し 死亡率が増加しました
- 幼児期に多重な逆境が起こると 早期成人期における死亡リスクが大きく上昇します
- これらの発見は 複数の逆境に直面している子どもを対象とした公衆衛生の介入の必要性を強調しています
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