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Updated: Dec 11, 2025

Measurement of Heme Synthesis Levels in Mammalian Cells
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ヘプシジン結合フェロポルチンの構造は,鉄の恒常化メカニズムを明らかにする

Christian B Billesbølle1, Caleigh M Azumaya2, Rachael C Kretsch3,4,5,6,7

  • 1Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA, USA.

Nature
|August 20, 2020
PubMed
まとめ

ヘプシジンはフェロポルチントランスポーターを分解して 鉄のレベルを制御します 新しい構造は,ヘプシディンが鉄を積んだフェロポルチンと結合し,鉄の恒常性を調節するために分解を狙うことを明らかにしています.

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