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Updated: Dec 11, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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IL4I1は,AHRを活性化し,腫瘍の進行を促進する代謝免疫チェックポイントです

Ahmed Sadik1, Luis F Somarribas Patterson2, Selcen Öztürk3

  • 1DKTK Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany; Faculty of Bioscience, Heidelberg University, 69120 Heidelberg, Germany.

Cell
|August 21, 2020
PubMed
まとめ

アリル炭水化物受容体 (AHR) を活性化し,がんの進行と免疫抑制を促進します. IL4I1を阻害することで 癌治療の新たな戦略が生まれます

キーワード:
AHR についてCLL についてIL4I1 についてT細胞の枯渇適応免疫アリル炭化水素受容体インタールイキン4誘発 1キヌレン酸トリプトファンの代謝腫瘍の微小環境

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