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Updated: Dec 11, 2025

Author Spotlight: Flow Cytometric Determination of Pyroptosis in Avian Cells
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サキナーションはガスダーミンDを無効化し,熱死を阻害する

Fiachra Humphries1, Liraz Shmuel-Galia1, Natalia Ketelut-Carneiro1

  • 1Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Science (New York, N.Y.)
|August 22, 2020
PubMed
まとめ

ディメチルフーマレート (DMF) はガスダーミンD (GSDMD) を改変し,細胞死を阻害することで,ピロプトーシスを防ぐ. この発見は 多発性硬化症のような 炎症性疾患に対する 新しい治療戦略を提供します

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