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Updated: Dec 11, 2025

Author Spotlight: Elucidating the Pathways of TFH Cell Differentiation in Acute LCMV Challenges
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SOSTDC1を産生する葉っぱヘルパーT細胞は,調節性葉っぱT細胞の分化を促進する

Xin Wu1, Yun Wang1, Rui Huang1

  • 1Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, P. R. China.

Science (New York, N.Y.)
|August 22, 2020
PubMed
まとめ

スクレロスティン領域を含むタンパク質1 (SOSTDC1) は,毛細管の調節性T細胞 (TFR) の生成に不可欠です. SOSTDC1はWNT-β-catenin経路を阻害し,TFR細胞の分化を促進し,生殖中心の反応を調節する.

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