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Updated: Dec 11, 2025

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells
10:21

Proliferation and Differentiation of Murine Myeloid Precursor 32D/G-CSF-R Cells

Published on: February 21, 2018

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ミエロイド細胞 トレムダウン 抗腫瘍反応

Aimée Bugler-Lamb1, Martin Guilliams1

  • 1Laboratory of Myeloid Cell Biology in Tissue Homeostasis and Regeneration, VIB-UGent Center for Inflammation Research, Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium.

Cell
|August 22, 2020
PubMed
まとめ

研究者らは,TREM2 (トリガリング受容体発現ミエロイド2) を阻害すると,抗腫瘍免疫が強化されると発見しました. TREM2阻害と免疫チェックポイント治療を併用すると,骨髄細胞を再プログラムすることで,腫瘍の成長が著しく減少します.

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Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo08:19

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