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Updated: Dec 10, 2025

Ookluc: A Plasmodium berghei Line for Identifying Transmission-blocking Compounds
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マラリア寄生虫のプラズモディウム・ファルシパラムへの糖分吸収を阻害する構造的基礎

Xin Jiang1, Yafei Yuan2, Jian Huang3

  • 1State Key Laboratory of Membrane Biology, Tsinghua University, Beijing 100084, China; Beijing Advanced Innovation Center for Structural Biology, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Joint Center for Life Sciences, Tsinghua University, Beijing 100084, China; School of Life Sciences, Tsinghua University, Beijing 100084, China.

Cell
|August 30, 2020
PubMed
まとめ

研究 者 たち は マラリア の 寄生虫 の 構造 を 解明 し た

キーワード:
PfHT1 についてプラズモディアム・ファルシパラムマラリア薬クリスタル構造グルコーストランスポーターヘキソストランスポーター阻害剤結合誘発ポケットマラリアの寄生虫オートステリックとアロステリックの二重阻害構造によって促進された薬物発見

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